Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
نویسندگان
چکیده
منابع مشابه
1. Nanostructured lipid carrier for bioavailability enhancement
Nanostructred lipid carrier(NLC) is second generation drug carrier system having solid matrix at room temperature. This carrier system is made up of physiological, biodegradable and biocompatible lipid materials and surfactants and is accepted by regulatory authorities for application in different drug delivery system. The main objective of this review is to explore the role of NLCs system for ...
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PURPOSE Nanostructured lipid carrier (NLC) is a useful delivery system with high capacity for bioactive loading, and suitable stability for fortification of foods and beverages. The objective of the present work is to prepare vitamin A palmitate (vitA)-loaded NLC and to investigate surfactant concentration effect on physicochemical properties of prepared formulation. METHODS VitA-loaded NLC w...
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The nanoparticle as a cancer drug delivery vehicle is rapidly under investigation due to its promising applicability as a novel drug delivery system for anticancer agents. This study describes the development, characterization and toxicity studies of a nanostructured lipid carrier (NLC) system for citral. Citral was loaded into the NLC using high pressure homogenization methods. The characteriz...
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Rosuvastatin is a lipid lowering agent, which has low solubility and low bioavailability of 20% with oral administration. Therefore the present study was undertaken to improve solubility and bioavailability of Rosuvastatin by formulating it into Nano structured lipid carriers (NLCs) by using stearic acid and Compritol ATO 888 as solid-lipid, Oleic acid as liquid-lipid and Poloxamer 188 as a sur...
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Purpose: Hyperpigmentation occurs when melanin is overproduced in certain spots on the skin and is one of the most challenging skin conditions to treat. Although it is usually harmless, for cosmetic reasons, it is dreadfully bothersome to those who undergo it. It was reported that N-acetyl-glucosamine (NAGA) prevents melanin synthesis and alters the expression of numerous genes related to pigme...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2016
ISSN: 1940-087X
DOI: 10.3791/53760